SAN FRANCISCO -- Yusmeiro Petit had all of an hour to prepare for his spot start, and he hadnt thrown off a mound for seven days while only playing catch. There was no time to study San Diegos hitters, either. Petit dazzled in place of injured ace Matt Cain, pitching six innings to lead the San Francisco Giants past the Padres 6-0 Tuesday night. "Thats my job," said Petit, who was one out from a perfect game last September against Arizona shortly after joining the rotation. "Im prepared for it any time for that, one moment before the game telling me youre going to start the game. Ive done it before. Its normal for me." Angel Pagan led off the first inning with a homer and Buster Posey connected two batters later to give Petit an early boost. Cain was scratched after cutting the tip of his right index finger. Cain was in the clubhouse kitchen making a sandwich and had a knife in his hand when the utensil dropped. Cain tried to catch it and cut his finger about a half-inch at the tip. He took batting practice, but then tried to throw and kept opening the cut. He expects to make his next start, Monday at Pittsburgh. "Its obviously really, really bad timing," Cain said. "Petit did an unbelievable job today. He picked it up and the guys scored a bunch of runs. Hopefully this isnt a big deal ... and it should be fine in a couple days." Petit (2-1) didnt allow a hit until Everth Cabreras leadoff single in the fourth. Hector Sanchez, starting at catcher with Posey at first base, hit a two-run single and a sacrifice fly. Petit allowed three hits with four strikeouts and no walks. It was his first start not allowing a run since he tossed a one-hitter last Sept. 6 at home against Arizona. He lowered his ERA from 3.68 to 2.61. Jean Machi pitched two innings and Santiago Casilla finished the 2-hour, 28-minute, three-hitter, San Franciscos second shutout this season. The Padres were blanked for the fourth time. The Giants said Cain wouldnt require stitches. "What a great effort," manager Bruce Bochy said of Petit. "Any time you lose your starter and the swing guy goes in there and gives you six innings like that, thats such a big lift for the club." Cain, who pitched a perfect game two years ago at AT&T Park, will finish winless in April. He is 0-3 with a 4.35 ERA in five starts. Pagan sent a 1-1 pitch from Eric Stults (1-3) just inside the left-field foul pole for his second homer, then Posey hit his sixth one out later. It was Pagans seventh career leadoff homer and first since May 1, 2013, at Arizona. The Giants hit two homers in the first inning at AT&T Park for the first time since Fred Lewis and Bengie Molina did so on July 22, 2008, against Washington. "Tonight I didnt execute many pitches. I was down in the zone the first time I played them," Stults said. "I knew they were probably going to be aggressive. They usually come out swinging early." Stults was done after 2 2-3 innings, allowing five runs and seven hits. San Diegos Yasmani Grandal made his first career start at first base as manager Bud Black gave struggling Yonder Alonso a break. San Diego will try to win Wednesdays rubber game for their first road series victory this year and snap a nine-series winless streak at AT&T Park dating to a three-game series here from Oct. 1-3, 2010, one that sealed the Giants division title on the way to the citys first World Series championship. NOTES: Padres reliever Donn Roach doubled in the sixth for his first major league hit. ... Home run king Barry Bonds made an appearance at the ballpark. ... Padres OF Seth Smith was available off the bench but missed his fourth straight start as he nurses a strained groin sustained Thursday night against the Nationals. Black said it was "a very good chance" he could start Wednesday. ... Giants RHP Tim Hudson tries for his fourth victory, facing LHP Robbie Erlin (1-3). ... The Giants improved to 11-1 when scoring first. ... 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And when you play a team that has that kind of transitional ability, thats not what you want to do." The Leafs carried the play for the majority of the first period and skated with desperation in the third, but ultimately couldnt break through the Blue Jackets defence. "For the first period we had lots of life and we were winning battles," said Leafs coach Randy Carlyle. "In the second period we just started to stall in the neutral zone. Were a team that needs to push the puck up the ice and establish a forecheck and we didnt do that for the first 13, 14 minutes of the second period." When the Leafs were able to apply some pressure, Sergei Bobrovsky was more than equal to the task. The Columbus goalie made 28 saves and stood especially tall when Toronto pushed for the tying goal in the final minutes of the game. "Their goalie made some really big saves in the third period and we missed some opportunities that we usually score on," said Leafs winger Joffrey Lupul. "We had some good chances, they just didnt go in." Its the Leafs third consecutive defeat since the Winter Olympics in Sochi, Russia. Toronto dropped overtime games on the road to the New York Islanders on Thursday and Montreal Saturday. "The three losses hurt because we had points available to us on the road," Carlyle said. "Thats the hard part, losing two overtime games on the road when we had one-goal leads in both games. That kind of kicks you a little bit, it doesnt feel very good." The Leafs remain in fifth place in the Eastern Conference, but five teams are within five or fewer points. "Obviously we wanted a different outcome in the past three games," Franson said. "But if you look at them we were sloppy on (Long) Island and still gave ourselves a chance to win. I thought we played a pretty decent game against Montreal, a couple of bounces and some penalty trouble cost us that one. "We didnt play a full 60 minutes tonight and thats on us. The other two games couldve gone either way." The loss against Columbus ended a seven-game home winning streak for Toronto, the Leafs longest at Air Canada Centre since a nine-game run in 2006-07. "We were rolling pretty good there and feeling quite confident in what we were doing (before the Olympic break)," Franson said. "When youre rolling like that, someetimes it can be difficult to find that smoothness in how you were performing before.dddddddddddd" The victory gives the Blue Jackets a sweep of the season series as Columbus beat Toronto 5-2 on Oct. 25 and thumped the Leafs 6-0 on Nov. 25. "They play a stingy game, they dont give you too much," Franson said. "They forecheck hard, they make you execute down low and if you dont youre going to get bit." Mason Raymond scored the lone goal for Toronto (32-23-8), making a game of it when he wired a slapshot past Bobrovsky at 15:45 of the third period. Thats as close as the Leafs would get, however, despite a late flurry when goalie James Reimer was pulled. "We didnt have enough of getting pucks through," Carlyle said. "It seemed like when we had glorious opportunities early in the game, they were blocking the shots. Later on, we stopped going to the front of the net and Bobrovsky had clear sightlines to make the saves." Reimer made 31 saves in a losing effort. It was his first start since Jan. 25. "I hadnt been in there for a while, so youre a little rusty and the games different than a practice, its faster, you have to battle harder through traffic," Reimer said. "There was a little rust there, but I felt pretty good." The teams were tied 0-0 after the first period and Columbus led 2-0 through 40 minutes. "They took over the game in the second period, they played really well, and we didnt find an answer soon enough," Lupul said. Reimer was sharp early as the Blue Jackets applied pressure, including a clear-cut breakaway by Columbus left-winger Nick Foligno less than for minutes into the game that was denied by the Leafs goalie. "We gave up two point-blank breakaways and Reimer stopped them both," Carlyle said. "You cant point to our goaltending as a deficiency, for sure. He did his part to give us a chance." Aided by a pair of power plays in the middle of the opening period, Toronto took over the momentum for the rest of the first period and had a handful of scoring chances but couldnt solve Bobrovsky. Prout opened the scoring when his slapshot from the left point beat a screened Reimer at 9:44 of the second. It was the defencemans first goal in 30 games this season and his second goal in 63 career NHL games. "Hes one of those guys that you root for and his teammates root for," said Blue Jackets coach Todd Richards. Anisimov gave the vistors a two-goal lead when he converted Nathan Hortons pass at the side of the crease at 12:38. Columbus went 0-for-1 on the power play while Toronto was 0-for-2. NOTES: The announced attendance at ACC was 19,577. a The Blue Jackets shut out the Leafs 6-0 at ACC in the last meeting between the two teams on Nov. 25, 2013. a Columbus defenceman Ryan Murray left with a lower-body injury in the first period and did not return. ' ' '